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Search Results for " apolipoprotein e "

Targets Recommended: Apoptosis

7

抑制剂 & 化合物

1

天然产物

29

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T30998L	COG-1410 acetate COG-1410 acetate(878009-24-6 Free base)	Apoptosis	Apoptosis
	COG-1410 acetate 是一种载脂蛋白 E 衍生肽，可用于神经系统疾病的研究。
T27957	LY-465608 LY 465608
	LY-465608, a PPAR Agonist, inhibits macrophage activation and atherosclerosis in apolipoprotein E knockout mice.
T30998	COG1410 COG-1410,COG 1410
	COG-1410 is an apolipoprotein E (apoE) peptide mimetic.
T69456	Melagatran monohydrate
	Melagatran monohydrate is a thrombin inhibitor. Melagatran prevents tissue factor expression in human platelet-monocyte heterotypic complexes. Melagatran reduces advanced atherosclerotic lesion size and may promote plaque stability in apolipoprotein E-deficient mice.
T75778	COG 133 TFA
	COG 133 TFA 是载脂蛋白 E (Apolipoprotein E, APOE) 肽的片段。COG 133 与 ApoE 全息蛋白竞争结合 LDL 受体，具有有效的抗炎和神经保护作用。COG 133 TFA 也是nAChR 拮抗剂，IC50为 445 nM。
T63355	BMS-309403 sodium
	BMS-309403 sodium 是一种有效的选择性脂肪细胞脂肪酸结合蛋白aFABP, 也称为FABP4，aP2抑制剂，对 FABP4，FABP3 和 FABP5 的Ki 分别为 <2 nM，250 nM，350 nM。BMS-309403 sodium 与蛋白质内部的脂肪酸结合口袋相互作用，竞争性地抑制内源性脂肪酸的结合。BMS-309403 sodium 可改善载脂蛋白E 缺乏症小鼠和培养的人内皮细胞的内皮功能。
T36521	Alaproclate (hydrochloride)
	Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s = 18, 4, 8, and 12 mg/kg, respectively).1 Alaproclate inhibits NMDA-evoked currents and depolarization-induced voltage-dependent potassium currents in rat hippocampal neurons (IC50s = 1.1 and 6.9 μM, respectively) and does not inhibit GABA-evoked currents when used at concentratio...

化合物

COG-1410 acetate

Cat.No: T30998L

Synonym: COG-1410 acetate(878009-24-6 Free base)

Target: Apoptosis

Cat.No: T27957

Synonym: LY 465608

Cat.No: T30998

Synonym: COG-1410,COG 1410

Melagatran monohydrate

Cat.No: T69456

Cat.No: T75778

BMS-309403 sodium

Cat.No: T63355

Alaproclate (hydrochloride)

Cat.No: T36521

Cat. No.	Product Name	Target	Signaling Pathways
T21383	D-Thyroxine Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine	Others	Others
	D-Thyroxine (Dextroxin) 是一种甲状腺激素，对 TSH 的分泌具有抑制作用，可用于研究高胆固醇血症。

天然产物

Cat.No: T21383

Synonym: Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00805	Apolipoprotein E/APOE Protein, Mouse, Recombinant (His) Apo-E,APOE,Apolipoprotein E	Mouse	HEK293 Cells
	Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. APOE is usually secreted in plasma. Phosphorylation sites are present in the extracellular medium.
TMPK-00788	Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc) apolipo E,Apo-E,Apolipoprotein E,APOE	Mouse	HEK293 Cells
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells wi...
TMPK-00589	Apolipoprotein E/APOE4 Protein, Human, Recombinant (His) APOE,apolipo E,Apo-E,APOE4,Apolipoprotein E	Human	HEK293 Cells
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells w...
TMPJ-00756	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His) Apolipoprotein E,Apo-E,APOE,ApoE3	Human	HEK293 Cells
	ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport .ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma .Apo...
TMPK-00762	Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc) APOE,Apo-E,Apolipoprotein E,APOE3,apolipo E	Human	HEK293 Cells
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells w...
TMPK-00588	Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc) Apolipoprotein E,Apo-E,apolipo E,APOE4,APOE	Human	HEK293 Cells
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells w...
TMPY-05297	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) LPG,apolipoprotein E,ApoE4,APO-E,LDLCQ5,AD2	Human	E. coli
	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPY-05528	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated APO-E,LDLCQ5,LPG,ApoE4,AD2,apolipoprotein E	Human	E. coli
	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPK-00763	Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated APOE3,Apo-E,apolipo E,Apolipoprotein E,APOE	Human	HEK293 Cells
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated i...
TMPH-03199	APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) APOE,Apolipoprotein E,Apo-E	Rabbit	E. coli
	APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.6 kDa and the accession number is P18287.
TMPH-02421	APOE Protein, Cynomolgus, Recombinant (His & Myc) Apolipoprotein E,Apo-E,APOE	Cynomolgus	E. coli
	APOE Protein, Cynomolgus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.0 kDa and the accession number is P10517.
TMPH-02901	SAA3 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA3 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.8 kDa and the accession number is P04918.
TMPH-03501	SAA1 Protein, Sheep, Recombinant (His)	Sheep	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Sheep, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.7 kDa and the accession number is P42819.
TMPH-00836	SAA1 Protein, Horse, Recombinant (His)	Horse	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Horse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 15.8 kDa and the accession number is P19857.
TMPH-00302	SAA1 Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.6 kDa and the accession number is P35541.
TMPH-00358	SAA1 Protein, Feline, Recombinant (B2M & His)	Feline	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Feline, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 24.1 kDa and the accession number is P19707.
TMPH-00501	SAA1 Protein, Canine, Recombinant (GST & His)	Canine	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Canine, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 42.5 kDa and the accession number is P19708.
TMPY-03428	Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (His) Apolipoprotein A-I	Human	E. coli
	Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.7 kDa and the accession number is P02647.
TMPJ-01447	Apolipoprotein B-100/APOB Protein, Human, Recombinant (His) APOB,ApolipoproteinB-100	Human	E. coli
	Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
TMPJ-00158	Apolipoprotein A-I/APOA1 Protein, Human, Recombinant Apolipoprotein A-I,APOA1,Apo-AI,ApoA-I	Human	E. coli
	Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including T...
TMPH-00947	APOC2 Protein, Human, Recombinant (His & SUMO) ApoC-II,APC2,Apolipoprotein C-II,Apolipoprotein...	Human	E. coli
	Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL. APOC2 Protein, Human, Recomb...
TMPY-02686	PON3 Protein, Human, Recombinant (S50N, His) paraoxonase 3	Human	Baculovirus Insect Cells
	PON3 was enriched in the mitochondria-associated membrane fraction of hepatocytes. PON3 deficiency resulted in impaired mitochondrial respiration, increased mitochondrial superoxide levels, and increased hepatic expression of inflammatory genes. PON3 deficiency did not influence atherosclerosis development on an apolipoprotein E null hyperlipidemic background, but it did lead to a significant 60% increase in atherosclerotic lesion size in Pon3KO mice on the C57BL/6J background when fed a cholate...
TMPK-01424	Peptide Ready HLA-E01:03&B2M Monomer Protein, Human, MHC (His & Avi) MHC,HLA-E01:03,Peptide Ready	Human	HEK293 Cells
	HLA-E01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01545	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated sHLA-E,MHC,MHC class I antigen E,HLAE,MHC HLA-E alpha-1,MHC ...	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01423	Peptide Ready HLA-E01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,Peptide Ready,HLA-E01:03	Human	HEK293 Cells
	HLA-E01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01541	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated QA1,MHC HLA-E alpha-2.1,MHC,HLAE,MHC class I antigen E,MHC H...	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01544	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi) MHC class I antigen E,HLAE,sHLA-E,QA1,MHC HLA-E alpha-2.1,MH...	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01452	HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi) HLAE,MHC class I antigen E,MHC,QA1,sHLA-E	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01514	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi) sHLA-E,MHC class I antigen E,MHC HLA-E alpha-1,MHC,HLAE,QA1,...	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...

重组蛋白

Apolipoprotein E/APOE Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00805

Species: Mouse

Expression System: HEK293 Cells

Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00788

Species: Mouse

Expression System: HEK293 Cells

Apolipoprotein E/APOE4 Protein, Human, Recombinant (His)

Cat.No: TMPK-00589

Species: Human

Expression System: HEK293 Cells

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00756

Species: Human

Expression System: HEK293 Cells

Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00762

Species: Human

Expression System: HEK293 Cells

Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00588

Species: Human

Expression System: HEK293 Cells

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)

Cat.No: TMPY-05297

Species: Human

Expression System: E. coli

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated

Cat.No: TMPY-05528

Species: Human

Expression System: E. coli

Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00763

Species: Human

Expression System: HEK293 Cells

APOE Protein, Rabbit, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03199

Species: Rabbit

Expression System: E. coli

APOE Protein, Cynomolgus, Recombinant (His & Myc)

Cat.No: TMPH-02421

Species: Cynomolgus

Expression System: E. coli

SAA3 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02901

Species: Mouse

Expression System: E. coli

SAA1 Protein, Sheep, Recombinant (His)

Cat.No: TMPH-03501

Species: Sheep

Expression System: E. coli

SAA1 Protein, Horse, Recombinant (His)

Cat.No: TMPH-00836

Species: Horse

Expression System: E. coli

SAA1 Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00302

Species: Bovine

Expression System: E. coli

SAA1 Protein, Feline, Recombinant (B2M & His)

Cat.No: TMPH-00358

Species: Feline

Expression System: E. coli

SAA1 Protein, Canine, Recombinant (GST & His)

Cat.No: TMPH-00501

Species: Canine

Expression System: E. coli

Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03428

Species: Human

Expression System: E. coli

Apolipoprotein B-100/APOB Protein, Human, Recombinant (His)

Cat.No: TMPJ-01447

Species: Human

Expression System: E. coli

Apolipoprotein A-I/APOA1 Protein, Human, Recombinant

Cat.No: TMPJ-00158

Species: Human

Expression System: E. coli

APOC2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00947

Species: Human

Expression System: E. coli

PON3 Protein, Human, Recombinant (S50N, His)

Cat.No: TMPY-02686

Species: Human

Expression System: Baculovirus Insect Cells

Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01424

Species: Human

Expression System: HEK293 Cells

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01545

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01423

Species: Human

Expression System: HEK293 Cells

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01541

Species: Human

Expression System: HEK293 Cells

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01544

Species: Human

Expression System: HEK293 Cells

HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01452

Species: Human

Expression System: HEK293 Cells

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01514

Species: Human

Expression System: HEK293 Cells

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